Arginines Plasma Concentration and Oxidative Stress in Mild to Moderate COPD
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چکیده
منابع مشابه
Arginines Plasma Concentration and Oxidative Stress in Mild to Moderate COPD
BACKGROUND Elevated plasma concentrations of the endogenous nitric oxide synthase (NOS) inhibitor asymmetric dimethylarginine (ADMA) have been observed in respiratory conditions such as asthma and cystic fibrosis. Since oxidative stress has been shown to increase the activity of arginine methylating enzymes, hence increased ADMA synthesis, and to reduce ADMA degrading enzymes, hence increased A...
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Being well-established in advanced chronic obstructive pulmonary disease (COPD), skeletal muscle dysfunction and its underlying pathology have been scarcely investigated in patients with mild-to-moderate airflow obstruction. We hypothesized that a loss of oxidative phenotype (oxphen) associated with decreased endurance is present in the skeletal muscle of patients with mild-to-moderate COPD. In...
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REFERENCES tion products correlated with markers of immune activation [1]. 5,6,7,8-Tetrahydrofolic acid, the biologically ac1. Galland R, Traeger J, Arkouche W, et al: Short daily hemodialysis tive cofactor, is very susceptible to oxidation, which may rapidly improves nutritional status in hemodialysis patients. Kidney Int 60:1555–1560, 2001 become relevant under oxidative stress conditions. Im...
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OBJECTIVE To assess and compare the prevalence of comorbidities and risk factors for cardiovascular disease (CVD) in COPD patients according to disease severity. METHODS The study included 25 patients with mild-to-moderate COPD (68% male; mean age, 65 ± 8 years; mean FEV1, 73 ± 15% of predicted) and 25 with severe-to-very severe COPD (males, 56%; mean age, 69 ± 9 years; mean FEV1, 40 ± 18% of...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0160237